PC1799

货号 规格 价格(¥)
PC1799S 50ul
PC1799M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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经典一抗-Glutamate receptor 3 Rabbit pAb

Datasheet

Background

L-Glutamate is the major excitatory neurotransmitter in the mammalian CNS, acting through both ligand gated ion channels (ionotropic receptors) and G-protein coupled (metabotropic) receptors. As such the glutamate receptors play a vital role in the mediation of excitatory synaptic transmission. The ionotropic glutamate receptors are multimeric assemblies of four or five subunits, and are subdivided into three groups (AMPA, NMDA and Kainate receptors) based on their pharmacology structural similarities Glutamate Receptor 3 is a ionotropic, AMPA-selective, membrane bound protein widely distributed in the CNS. Predominant expression is seen in the neuronal cells of the cerebral cortex, dentate gyrus, and glial cells throughout brain regions. AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. Glutamate Receptor 3 exists in 2 named isoforms - Flip and Flop, produced by alternative splicing.

Alternative Names

AMPA 3; AMPA selective glutamate receptor 3; AMPA-selective glutamate receptor 3; GluA3; GLUK3; GLUR 3; GLUR C; GLUR K3; GluR-3; GluR-C; GluR-K3; GLUR3; GLURC; Glutamate receptor 3; Glutamate receptor C; Glutamate Receptor Ionotrophic AMPA 3; Glutamate receptor ionotropic; Glutamate receptor subunit 3; GRIA 3; Gria3; GRIA3_HUMAN; GRM 3; Ionotrophic Glutamate Receptor; Metabotropic glutamate receptor 3 precursor; mGlu 3; MGLUR 3; MRX94.

Reactivity

Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit

Application

IHC,IF,ICC

Recommended Dilution

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400

Application Image

Mol Weight

98kD

Gene ID

2892

UniProt

P42263

Uniprot link

Subcellular location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Interaction with CNIH2 and CNIH3 promotes cell surface expression (By similarity).

Specificity

Immunogen

KLH conjugated synthetic peptide derived from human GLUR3

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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