PC1645

货号 规格 价格(¥)
PC1645S 50ul
PC1645M 100ul

以上产品均有现货供应

订购咨询 orders@ab-mart.com

订货热线 4006-123-828

技术支持15618194176

经销商名录:点击查看


Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-phospho-Erk1 (Thr202 + Tyr204) Rabbit pAb

Datasheet

Background

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

Alternative Names

Erk1 (pT202/pY204); ERK/MAPK(phospho T202/Y204); ERK1 (phospho T202); p-ERK1 (phospho T202); p44/42 MAP Kinase(Phospho-Thr202); ERK;
ERK-1;
ERT 2;
ERT2;
Extracellular Signal Regulated Kinase 1;
Extracellular signal related kinase 1;
Extracellular signal-regulated kinase 1;
HGNC6877;
HS44KDAP;
HUMKER1A;
Insulin Stimulated MAP2 Kinase;
Insulin-stimulated MAP2 kinase;
MAP kinase 1;
MAP kinase 3;
MAP Kinase;
MAP kinase isoform p44;
MAPK 1;
MAPK 3;
MAPK;
MAPK1;
Mapk3;
MGC20180;
Microtubule Associated Protein 2 Kinase;
Microtubule-associated protein 2 kinase;
Mitogen Activated Protein Kinase 3;
Mitogen-activated protein kinase 1;
Mitogen-activated protein kinase 3;
MK03_HUMAN;
OTTHUMP00000174538;
OTTHUMP00000174541;
p44 ERK1;
p44 MAPK;
p44-ERK1;
p44-MAPK;
P44ERK1;
P44MAPK;
PRKM 3;
PRKM3;
Protein Kinase Mitogen Activated 3.

Reactivity

Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit,GuineaPig

Application

IHC,IF,ICC,FC

Recommended Dilution

IHC 1:100-500
IF 1:100-500
ICC 1:100-1:400
FC 1:100

Application Image

Mol Weight

43kD

Gene ID

5595

UniProt

Q63844

Uniprot link

Subcellular location

Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, centrosome. Cytoplasm. Note=Associated with the spindle duringprometaphase and metaphase. PEA15-binding andphosphorylated DAPK1 promote its cytoplasmic retention.Phosphorylation at Ser-244 and Ser-246 as well asautophosphorylation at Thr-188 promote nuclear localization.

Specificity

Widely expressed.

Immunogen

KLH conjugated Synthesised phosphopeptide derived from rat ERK1 around the phosphorylation site of Thr201/204

Source

Rabbit

Clonality

Polyclonal

Isotype

IgG

Purification

affinity purified by Protein A

Formulation

Liquid

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Concentrate

Storage Condition

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

46c73bc4c7a4d51a3ce472aedb80205b_compress.jpg

      微信客服

沪ICP备17056956号-2    艾比玛特医药科技(上海)有限公司