Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
ABC transporter;
ABC15;
ABCG 2;
ABCG2;
ABCG2_HUMAN;
ABCP;
ATP binding cassette sub family G (WHITE) member 2;
ATP binding cassette transporter G2;
ATP-binding cassette sub-family G member 2;
BCRP;
BCRP1;
BMDP;
Breast cancer resistance protein;
CD338;
CDw338;
CDw338 antigen;
EST157481;
GOUT1;
MGC102821;
Mitoxantrone resistance associated protein;
Mitoxantrone resistance-associated protein;
MRX;
Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2;
MXR;
MXR1;
Placenta specific ATP binding cassette transporter;
Placenta specific MDR protein;
Placenta-specific ATP-binding cassette transporter;
UAQTL1.
Human,Rat,Mouse
IF,ICC,FC
IF 1:100ICC 1:100-1:400FC 3ug/test
72kD
9429
Q9UNQ0
Cell membrane; Multi-pass membrane protein.
Highly expressed in placenta. Low expression in small intestine, liver and colon.
KLH conjugated synthetic peptide derived from human ABCG2
Rabbit
Polyclonal
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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