Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
FRIGG ,
KIAA0668 ,
nuclear envelope protein ,
Protein unc-84 homolog B ,
Rab5 interacting protein ,
RAB5IP ,
Sad1 and UNC84 domain containing 2 ,
Sad1 unc-84 domain protein 2 ,
Sad1 unc84 domain protein ,
Sad1/unc-84 protein-like 2 ,
Sad1/unc84 protein-like ,
SUN domain-containing protein 2 ,
UNC 84B ,
unc84 homolog B (C. elegans) ,
unc84 homolog B ,
unc84, C. elegans, homolog of, B ,
UNC84B
Rat,Human,Mouse
WB,IHC,IF,ICC
WB 1:500-2000IHC 1:100-500IF 1:100-1:400ICC 1:100-1:400
80kD
25777
Q9UH99
Widely expressed. Highly expressed in heart, lung and muscle. Weakly expressed in fetal heart. Slightly overexpressed in some heart tissues form patients with congenital heart defects.
Recombinant protein within human SUN2 aa 500-700.
Rabbit
Recombinant
IgG
affinity purified by Protein A
Liquid
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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