There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]

Alkaline phosphatase; Alkaline phosphatase placental; Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; ALP; Alp1; ALPP; FLJ61142; Germ-cell alkaline phosphatase; nagao isozyme; OTTHUMP00000164354; PALP; Placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; placental type; PLAP; PLAP-1; PLAP1; PPB1_HUMAN.

Human

WB

WB 1:1000-1:2000

53kD

250

P05187

https://www.uniprot.org/uniprotkb/P05187

Cell membrane; Lipid-anchor, GPI-anchor.

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

KLH conjugated synthetic peptide derived from human Placental alkaline phosphatase

Mouse

Monoclonal

IgG1/kappa

affinity purified by Protein A

Liquid

Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.