Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Requires the presence of the other members of the gamma-secretase complex for protease activity.Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
AD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182.
Human,Mouse,Rat
WB,IHC,IF,ICC,FC
WB 1:1000-1:2000IHC 1:50-200IF 1:100-1:400ICC 1:100-1:400FC 1:100
53kD
5663
P49769
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell surface. Note=Bound to NOTCH1 also at the cell surface. Colocalizes with CDH1/2 at sites of cell-cell contact. Colocalizes with CTNNB1 in the endoplasmic reticulum and the proximity of the plasma membrane. Also present in azurophil granules of neutrophils.
Expressed in a wide range of tissues including various regions of the brain, liver, spleen and lymph nodes.
KLH conjugated synthetic peptide derived from human Presenilin 1
Rabbit
Recombinant
IgG
affinity purified by Protein A
Liquid
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
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