Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.
MCAK; KNSL6.
Human
WB,IF,ICC,FC
WB 1:1000-1:2000IF 1:100-1:400ICC 1:100-1:400FC 1:100
81kD
11004
Q99661
Cytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2.
Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific.
KLH conjugated synthetic peptide derived from human KIF2C
Rabbit
Recombinant
IgG
affinity purified by Protein A
Liquid
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
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