Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. {ECO:0000269|PubMed:10540332, ECO:0000269|PubMed:9207005, ECO:0000269|PubMed:9469461, ECO:0000269|PubMed:9521068}.
P51685
1237
Transmembrane
41kD
C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198),CKRL1 CMKBR8 CMKBRL2
Human
FC
FC 1:50
Monoclonal
Mouse
Mouse IgG2c,κ
Affinity-chromatography
Liquid
1*PBS with 50% glycerol
0.5mg/ml
Store at -20°C long term.
Human CCR8 (CD198)-transfected cells
![]() | The binding affinity of purified CCR8 (clone 101E4) against CCR8 expressing cells. The results showed that 101E4 bound to the human CCR8 overexpressing 293T cells with an EC50 of 0.41 nM, but without any binding to parental 293T cells. |
![]() | Purified CCR8 (clone 101E4) concentration dependently inhibited the CCR8-mediated β-arrestin signaling, with an IC50 of 41 ng/ml. |
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