Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3a (86 kDa) and Stat3
APRF; HIES; FLJ20882; MGC16063; STAT3
p40763
6774
Human,Mouse,Monkey
WB,IHC,IF,ICC
WB 1:500-1:1000IHC 1:200-1:1000IF 1:100-1:400ICC 1:200-1:1000
Mouse IgG1
Mouse
Purified recombinant fragment of human STAT3 expressed in E. Coli.
88kDa
PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.
Store at 4℃ short term. Store at -20℃ long term. Avoid freeze / thaw cycle.
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