The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra

p26951

3563

Human

IHC,IF,ICC,FC

IHC 1:200-1:1000
IF 1:100-1:400
ICC 1:200-1:1000
FC 1:200-1:400

Mouse IgG1

Mouse

Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.

43.3kDa

PBS, pH 7.4, 40% glycerol, and 0.01% sodium azide.

Store at 4℃ short term. Store at -20℃ long term. Avoid freeze / thaw cycle.