The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.

Zinc fingers and homeoboxes protein 2
Alpha-fetoprotein regulator 1 (AFP regulator 1)
Regulator of AFP
Zinc finger and homeodomain protein 2
ZHX2
AFR1, KIAA0854, RAF

q9y6x8

WB,IF,ICC

WB 1:1000
IF 1:100-1:400
ICC 1:100

Human,Mouse,Rat,Monkey

Predicted size: 92 kDa

Rabbit

Nucleus.

Protein A affinity purified.

Recombinant Rabbit monoclonal

IgG

Liquid

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.