t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. When cloned and expressed in E.coli, where protein palmitoylation does not occur, Cys-85, Cys-88, Cys-90 and Cys-92 in the protein sequence readily form an iron-sulfur cluster. Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.

Synaptosomal-associated protein 25
SNAP-25
Super protein (SUP)
Synaptosomal-associated 25 kDa protein
SNAP25
SNAP

p60880

WB,IHC,IF,ICC,FC

WB 1:2000
IHC 1:500-1:5000
IF 1:100-1:400
ICC 1:100
FC 1:1000

Human,Mouse,Rat

Predicted size: 23 kDa

Rabbit

Cytoplasm, perinuclear region. Cell membrane.

Protein A affinity purified.

Recombinant Rabbit monoclonal

IgG

Liquid

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.