Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
The Na-K-2Cl cotransporter (NKCC2) is a sodium-potassium-chloride cotransporter. It is mainly expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle''s loop (TALH) and mediates the majority of NaCl resorption and concentration of urine. NKCC2 is the target for several diuretic drugs, such as bumetanide, and is involved in the pathogenesis of hypertension. Mutations in the NKCC2-encoding gene, SLC12A1, causes Bartter’s syndrome, which is featured by impaired salt reabsorption in the TALH, hypokalemic metabolic alkalosis, and hypercalciuria . Recently, NKCC2 was reported to be expressed in the brain hypothalamo-neurohypophyseal system (HNS) and upregulated upon osmotic stress.
Solute carrier family 12 member 1
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
Kidney-specific Na-K-Cl symporter
SLC12A1
NKCC2
q13621
WB,IHC,IF,ICC
WB 1:2000IHC 1:20000IF 1:100-1:400ICC 1:100
Human,Mouse,Rat
Predicted size: 121 kDa
Rabbit
Cell membrane
Protein A affinity purified.
Recombinant Rabbit monoclonal
IgG
Liquid
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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订购专线:4006-123-828
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