CD32A: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. CD32B: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. CD32C: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.

Low affinity immunoglobulin gamma Fc region receptor II-a
Low affinity immunoglobulin gamma Fc region receptor II-b
Low affinity immunoglobulin gamma Fc region receptor II-c
IgG Fc receptor II-a
IgG Fc receptor II-b
IgG Fc receptor II-c
CDw32
Fc-gamma RII-a (Fc-gamma-RIIa; FcRII-a)
Fc-gamma RII-b (Fc-gamma-RIIb; FcRII-b)
Fc-gamma RII-c (Fc-gamma-RIIc; FcRII-c)
CD32
FCGR2A
FCGR2B
FCGR2C
CD32, FCG2, FCGR2A1, IGFR2

p12318

WB,IHC

WB 1:1000
IHC 1:500-1:2000

Human

Predicted size: 35 kDa

Rabbit

Cell membrane.

Protein A affinity purified.

Recombinant Rabbit monoclonal

IgG

Liquid

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.