S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene.It is also known as calgranulin A.The proteins S100A8 and S100A9 form a heterodimer called calprotectin.The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis and post COVID-19 condition.

CAGA, CFAG, MRP8

p05109

WB,IHC,IF,ICC,IP,FC

WB 1:2000-1:5000
IHC 1:10000
IF 1:1000-1:3000
ICC 1:50000
IP 1-2μg/sample
FC 1:1000

Human

Predicted size: 11 kDa

Rabbit

Secreted;
Cytoplasm;
Cytoplasm, cytoskeleton;
Cell membrane.

Protein A affinity purified.

Recombinant Rabbit monoclonal

IgG

Liquid

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.