Synaptic vesicle glycoprotein 2A (SV2A) is a transmembrane protein belonging to a family of keratan sulfate proteoglycans, located on the synaptic vesicles of mammalian neuronal and endocrine cells. It''s encoded by the SV2A gene. SV2A is the most widely expressed isoform of the SV2 family (which also includes the SV2B and SV2C proteins) found in all brain regions. The role of the SV2 proteins is not well understood, however they are thought to be involved in regulating vesicular processes. The SV2A protein is a target of the anti-epileptic drugs (anticonvulsants) levetiracetam and brivaracetam but it is not clear how these drug affect SV2A activity.

Synaptic vesicle glycoprotein 2A
Synaptic vesicle protein 2; Synaptic vesicle protein 2A
Calcium regulator SV2A
Sv2a
Kiaa0736, Sv2

q7l0j3

WB,IHC,IF,ICC,IP

WB 1:5000
IHC 1:500-1:2000
IF 1:500
ICC 1:100-1:400
IP 1-2μg/sample

Human,Mouse,Rat,Cynomolgus monkey,Pig

Rabbit

Predicted size: 83 kDa

Presynapse, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane.

Recombinant Rabbit monoclonal

IgG

Protein A affinity purified.

Liquid

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.