Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 is an enzyme that in humans is encoded by the PIN1 gene. Pin 1, or peptidyl-prolyl cis/trans isomerase (PPIase), isomerizes only phospho-Serine/Threonine-Proline motifs. The enzyme binds to a subset of proteins and thus plays a role as a post phosphorylation control in regulating protein function. Studies have shown that the deregulation of Pin1 may play a pivotal role in various diseases. Notably, the up-regulation of Pin1 is implicated in certain cancers, and the down-regulation of Pin1 is implicated in Alzheimer''s disease. Inhibitors of Pin1 may have therapeutic implications for cancer and immune disorders.
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Peptidyl-prolyl cis-trans isomerase Pin1 (PPIase Pin1)
Rotamase Pin1
PIN1
q13526
WB,IHC,IF,ICC,IP
WB 1:2000IHC 1:50-1:1000IF 1:100-1:400ICC 1:100IP 1-2μg/sample
Human,Mouse,Rat
Rabbit
Predicted size: 18 kDa
Nucleus, Nucleus speckle, Cytoplasm.
Recombinant Rabbit monoclonal
IgG
Protein A affinity purified.
Liquid
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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