Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Prelamin-A/C, or lamin A/C is a protein that in humans is encoded by the LMNA gene. Lamin A/C belongs to the lamin family of proteins. DNA double-strand damages can be repaired by either homologous recombination (HR) or non-homologous end joining (NHEJ). LMNA promotes genetic stability by maintaining the levels of proteins that have key roles in HR and NHEJ. Mouse cells that are deficient for maturation of prelamin A have increased DNA damage and chromosome aberrations, and show increased sensitivity to DNA damaging agents. In progeria, the inadequacy of DNA repair, due to defective LMNA, may cause features of premature aging (see DNA damage theory of aging).
Prelamin-A/C
Lamin A/C
70 kDa lamin, Renal carcinoma antigen NY-REN-32
LMNA
LMN1
p02545
WB,IHC
WB 1:2000IHC 1:2000-1:4000
Human,Mouse,Rat
Rabbit
Predicted size: 74 kDa
Nucleus lamina, Nucleus envelope, nucleoplasm, Nucleus matrix; Nucleus speckle.
Recombinant Rabbit monoclonal
IgG
Protein A affinity purified.
Liquid
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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