Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP proteins are highly expressed in the mammalian reproductive tract and in the venom secretory ducts of some reptiles. CRISP-11 (cysteine-rich secretory protein 11), also known as cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2 or LCRISP2), is a 497 amino acid protein containing 2 LCCL domains, which are thought to function as autonomous folding domains used to construct modular proteins through exon shuffling. Serum concentrations of CRISP-11 have been shown to be an indicator of a patient's exposure to lipopolysaccahride (LPS), the immunostimulatory component of Gram-negative bacteria, and can determine one's sensitivity to it.

Cysteine-rich secretory protein LCCL domain-containing 2 (Cysteine-rich secretory protein 11) (CRISP-11) (LCCL domain-containing cysteine-rich secretory protein 2) CRISPLD2 CRISP11 LCRISP2 UNQ2914/PRO1156/PRO9783

CRISPLD2 Antibody detects endogenous levels of total CRISPLD2.

Human, Mouse, Rat

Mouse

56 kDa

WB 1:1000-1:2000
IHC 1:50-1:200
IF 1:100-1:400
ICC 1:100-1:400
IP 1:50

Store at -20 °C. Stable for 12 months from date of receipt.