Exhibits acyltransferase activity . Exhibits acetyltransferase activity . Activity is calcium-independent . Catalyzes the conversion of lysophosphatidylcholine into phosphatidylcholine . Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate into 1,2-diacyl-sn-glycerol-3-phosphate by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively . Involved in platelet-activating factor biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine . May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology . Involved in the regulation of lipid droplet number and size .

Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)

q8nf37

Human

WB,IHC,IF,ICC,IP,FC

WB 1:1000
IHC 1:200-1:2000
IF 1:100-1:200
ICC 1:100-1:200
IP 1:20-1:50
FC 1:20-1:50

~60 kD

Rabbit

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at -20°C. Stable for 12 months from date of receipt.