Polyamine deacetylase , which acts preferentially on N-acetylspermidine, and also on acetylcadaverine and acetylputrescine . Exhibits attenuated catalytic activity toward N,N-diacetylspermidine and very low activity, if any, toward N-acetylspermidine . Histone deacetylase activity has been observed in vitro . Has also been shown to be involved in MSH2 deacetylation . The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak . May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells . May play a role in homologous recombination . May promote DNA mismatch repair .

Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)

q969s8

Human

WB,IF,ICC,IP,FC

WB 1:1000
IF 1:100-1:200
ICC 1:100-1:200
IP 1:100
FC 1:100-1:200

~72 kD

Rabbit

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at -20°C. Stable for 12 months from date of receipt.