Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Integrin ITGA4/ITGB7 is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue . Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract . Also interacts with VCAM1 and fibronectin, an extracellular matrix component . It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin . Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin . Integrin ITGAE/ITGB7 is a receptor for E-cadherin . ; Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120.
Integrin beta-7 (Gut homing receptor beta subunit)
p26010
Human
WB
WB 1:1000-1:5000
~87 kD
Rabbit
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Store at -20°C. Stable for 12 months from date of receipt.
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