TB6418

货号 规格 价格(¥)
TB6418S 50μl
TB6418M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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   蛋白质印迹

   免疫荧光

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Mov10 antibody

Datasheet

Background

5' to 3' RNA helicase that is involved in a number of cellular roles ranging from mRNA metabolism and translation, modulation of viral infectivity, inhibition of retrotransposition, or regulation of synaptic transmission . Plays an important role in innate antiviral immunity by promoting type I interferon production . Mechanistically, specifically uses IKKepsilon/IKBKE as the mediator kinase for IRF3 activation . Blocks HIV-1 virus replication at a post-entry step . Counteracts HIV-1 Vif-mediated degradation of APOBEC3G through its helicase activity by interfering with the ubiquitin-proteasome pathway . Also inhibits hepatitis B virus/HBV replication by interacting with HBV RNA and thereby inhibiting the early step of viral reverse transcription . Contributes to UPF1 mRNA target degradation by translocation along 3' UTRs . Required for microRNA -mediated gene silencing by the RNA-induced silencing complex . Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC . In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 . Restricts retrotransposition of long interspersed element-1 in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 . Facilitates LINE-1 uridylation by TUT4 and TUT7 . Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol . May function as a messenger ribonucleoprotein clearance factor . ; Required for RNA-directed transcription and replication of the human hepatitis delta virus . Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.

Alternative Name

Helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein)

Uniprot

q9hce1

Reactivity

Human,Mouse,Rat

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:1000
IHC 1:50-1:100

Mol Weight

~114 kD

Source

Rabbit

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage

Store at -20°C. Stable for 12 months from date of receipt.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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