Transcription factor . Associated with the BAF SWI/SNF chromatin remodeling complex . Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene . Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin level . Involved in brain development . May play a role in hematopoiesis . Essential factor in lymphopoiesis required for B-cell formation in fetal liver . May function as a modulator of the transcriptional repression activity of NR2F2 .

B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)

q9h165

Human,Mouse,Rat

WB,IHC,IF,ICC,FC

WB 1:2000-1:20000
IHC 1:50-1:100
IF 1:200-1:500
ICC 1:200-1:500
FC 1:200

~92 kD

Rabbit

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Store at -20°C. Stable for 12 months from date of receipt.