PW13917

货号 规格 价格(¥)
PW13917S 50μl
PW13917M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-PDE4D antibody

Datasheet

Background

Phosphodiesterases (PDE) hydrolyze cAMP to 5’AMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both
UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4D gene maps to chromosome 5q12.

Alternative Names

cAMP-specific 3'',5''-cyclic phosphodiesterase 4D; DPDE3; PDE43; PDE4D; DPDE3

Uniprot

q08499

Reactivity

Human,Mouse,Rat

Application

WB,IHC

Application Image

Recommended Dilution

WB 1:500-1:1000
IHC 1:50-1:200

Mol Weight

~ 91 kDa

Source

Rabbit

Specificity

This antibody detects endogenous levels of PDE4D protein.

Immunogen

Synthetic peptide, corresponding to amino acids 30-70 Human PDE4D.

Clonality

Polyclonal

Isotype

Rabbit IgG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Concentration

1mg/ml

Storage

Store at 4℃ short term,and store at -20℃ long term. Avoid freeze-thaw cycles.

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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