C/EBP family members include C/EBP α, C/EBP β, C/EBP γ, C/EBP δ, C/EBP ε and C/EBP ζ, all of which are capable of forming homodimers or heterodimers with each other. C/EBP ζ, also known as CBF2, NOC1, CHOP10 (C/EBP homologous protein 10), GADD153 (growth arrest and DNA damage-inducible gene 153) or HSPCBF, is a ubiquitously expressed 1,054 amino acid protein that localizes to the nucleus and regulates transcription. More specifically, C/EBP ζ is believed to play a role regulating the expression of CRP (C-reactive protein). Unlike most C/EBP dimers, C/EBP ζ-containing dimers do not bind the classical C/EBP-binding consensus sequence. Rather, C/EBP ζ-containing dimers must associate with RBP-Jκ (another transcription factor) in order to accomplish binding to the C/EBP site.

CBF2; CCAAT binding factor; CCAAT box binding transcription factor; CCAAT/enhancer binding protein zeta; Cebpz; HSPCBF; CBF;

q03701

Human,Mouse,Rat

WB,IHC

WB 1:500-1:1000
IHC 1:50-1:200

~121 kDa

Rabbit

This antibody detects endogenous levels of C/EBP ζ protein.

Synthetic peptide, corresponding to the N-terminus of Human C/EBP ζ.

Polyclonal

Rabbit IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1mg/ml

Store at 4℃ short term,and store at -20℃ long term. Avoid freeze-thaw cycles.