G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR68 (G protein-coupled receptor 68), also known as OGR1 (ovarian cancer G-protein coupled receptor 1), is a 365 amino acid multi-pass membrane protein that is expressed in testis, spleen, lung, brain and placenta. Existing as a member of the G protein-coupled receptor family, GPR68 functions as a high affinity receptor for sphingosylphosphorylcholine and is coupled to G proteins that enhance phosphoinositide hydrolysis.

G protein coupled receptor 68; G-protein coupled receptor 68; GPR 12A; GPR 68; GPR12A; Gpr68; OGR 1; OGR-1; OGR1; OGR1; Ovarian cancer G protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor

q15743

Human,Mouse,Rat

WB

WB 1:500-1:1000

~41 kDa

Rabbit

This antibody detects endogenous levels of GPR68 protein.

Synthetic peptide, corresponding to amino acids 183-232 of Human GPR68.

Polyclonal

Rabbit IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1mg/ml

Store at 4℃ short term,and store at -20℃ long term. Avoid freeze-thaw cycles.