PW17251

货号 规格 价格(¥)
PW17251S 50μl
PW17251M 100μl

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-MEK-7 (phospho-S271) polyclonal antibody

Datasheet

Background

MKK7 is a MAP kinase kinase that serves as a specific activator of the SAPK/JNK pathway. MKK7 is strongly activated by TNF-α, as well as other environmental stresses, whereas SEK1/MKK4, which activates both p38 and SAPK/JNK pathways, is not activated by TNF-α. Sequence alignment of the activation loop of the MAP kinase kinase family members indicates that Ser271 and Thr275 are potential phosphorylation sites that are crucial for the kinase acivity.

Alternative Names

Mitogen Activated Protein Kinase kinase 7; c-Jun N-terminal kinase kinase 2; JNK activating kinase 2; Jnkk 2; Jnkk2; MAP2K7; MAPKK-7; MKK 7; MKK-7; PRKMK 7; PRKMK7; Sek-2; Dual specificity mitogen activated protein kinase kinase 7; JNK kinase 2; Jnkk

Uniprot

o14733

Reactivity

Human,Rat,Mouse

Application

WB

Application Image

Recommended Dilution

WB 1:500-1:1000

Mol Weight

~ 48 kDa

Source

Rabbit

Specificity

MEK-7 (phospho-S271) polyclonal antibody detects endogenous levels of MEK-7 protein only when phosphorylated at Ser271.

Immunogen

Synthetic phosphopeptide derived from human MEK-7 around the phosphorylation site of Serine 271

Clonality

Polyclonal

Isotype

Rabbit IgG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Concentration

1mg/ml

Storage

Store at 4℃ short term,and store at -20℃ long term. Avoid freeze-thaw cycles.

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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