The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]

platelet endothelial cell adhesion molecule precursor-1; PECAM-1; PECAM1; Adhesion molecule; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; Pecam 1; PECA1_HUMAN; PECAM 1 CD31 EndoCAM; PECA1; Pecam1; Platelet endothelial cell adhesion molecule; Platelet/endothelial cell adhesion molecule 1; Adhesion molecule; Platelet/endothelial cell adhesion molecule.

p16284

5175

PECAM1

Mouse,Rat,Human

WB

WB 1:500-2000

78kD

Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells (PubMed:18388311, PubMed:21464369).
Expressed in human umbilical vein endothelial cells (HUVECs) (at protein level) (PubMed:19342684, PubMed:17580308).
Expressed on neutrophils (at protein level) (PubMed:17580308).
Isoform Long predominates in all tissues examined (PubMed:12433657).
Isoform Delta12 is detected only in trachea (PubMed:12433657).
Isoform Delta14-15 is only detected in lung (PubMed:12433657).
Isoform Delta14 is detected in all tissues examined with the strongest expression in heart (PubMed:12433657).
Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U-937 histiocytic lymphoma cell lines (at protein level) (PubMed:12433657, PubMed:18388311).

Rabbit

KLH conjugated synthetic peptide derived from human CD31（aa 501-600/738）

Polyclonal

IgG

affinity purified by Protein A

Liquid

1mg/ml

Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.