Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ACTN 1; ACTN1_HUMAN; alpha Actinin 1; alpha actinin cytoskeletal isoform; alpha-actinin cytoskeletal isoform; alpha-actinin-1; FLJ40884; FLJ54432; Actinin alpha 1; F-Actin Cross-Linking Protein; Non-Muscle alpha-Actinin-1; Actinin, alpha 1; Actinin 1 Smooth Muscle; BDPLT15;
p12814
87
ACTN1
Human,Mouse,Rat
WB
WB 1:500-2000
103kD
Rabbit
Recombinant human Alpha-actinin-1 protein
Polyclonal
IgG
affinity purified by Protein A
Liquid
1mg/ml
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
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