13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates ''Ser-15'' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806).
EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase)
TP53RK C20orf64 PRPK BUD32; C20orf64; dJ101A2; Nori-2; Nori-2p; PRPK
Q96S44
Human, Mouse, Rat
WB,IHC
WB 1:2000IHC 1:150
28 kDa
Mouse
Full length human recombinant protein of human TP53RK (NP_291028) produced in E.coli.
Monoclonal
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at -20 °C. Stable for 12 months from date of receipt.
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