Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP . Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives . Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear . Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs . May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA . Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
NUDT15;MTH2
q9nv35
Human,Mouse,Rat
WB
WB 1:2000
Monoclonal
18.4 kDa
Mouse
Full length human recombinant protein of human NUDT15 (NP_060753) produced in HEK293T cell.
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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