Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response . Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response . Increases IL-8 transcription . Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses such as SARS-CoV-2, SARS-CoV and HIV-1, induces IL1B release through NLRP3 inflammasome activation . MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
MYD88;MYD88D
q99836
Human
WB,IHC,FC
WB 1:2000IHC 1:150FC 1:100
Monoclonal
33.1 kDa
Mouse
Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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