Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Histone H4,H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4

P62805,P62806,P62804

121504/554313/8294/8359/8360/8361/8362/8363/8364/8365/8366/8367/8368/8370/1.00041e+008/1.00361e+008

Human,Mouse,Rat,Monkey

WB,IHC,IF,ICC,ELISA

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:100-1:400
ICC 1:100-1:400
ELISA 1:10000

Acetyl-Histone H4 (K12) Polyclonal Antibody detects endogenous levels of Histone H4 protein only when acetylated at K12.

11kDa

Rabbit

The antiserum was produced against synthesized peptide derived from human Histone H4 around the acetylated site of Lys12. AA range:10-59

Polyclonal

Rabbit,IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1 mg/ml

Store at -20℃. Stable for 12 months from date of receipt.