Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation . Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles . Has a a strong preference for acetylation of H3 at ''Lys-9'' (H3K9ac) . Also acetylates non-histone proteins, such as ACLY, MAPRE1/EB1, PLK4, RRP9/U3-55K and TBX5 . Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A . Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-BMAL1 and CLOCK-BMAL1 heterodimers . Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 . Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 . Acetylates RRP9/U3-55K, a core subunit of the U3 snoRNP complex, impairing pre-rRNA processing . Acetylates MAPRE1/EB1, promoting dynamic kinetochore-microtubule interactions in early mitosis . Also acetylates spermidine . .; (Microbial infection) In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat''s transactivating activity and may help inducing chromatin remodeling of proviral genes. .
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57),KAT2B PCAF
Q92831,Q9JHD1
8850/18519
Human,Mouse
WB,IHC
WB 1:500-2000IHC 1:50-300
Acetyl-PCAF (K428) Polyclonal AntibodySynthesized peptide derived from the human PCAF around the acetylation site of K428.
93kDa
Rabbit
Synthesized acetyl-peptide derived from the human PCAF around the acetylation site of K428.
Polyclonal
Rabbit,IgG
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
1 mg/ml
Store at -20℃. Stable for 12 months from date of receipt.
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应聘职位:hr@ab-mart.com
订购专线:4006-123-828
销售电话:13916964679(微信同号)
技术支持:15618194176(微信同号)
华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:
陆经理:手机13122837132(微信同号)
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张经理:手机13122150513(微信同号)

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