Membrane-bound E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins . May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4 . Mediates ubiquitination of PXN/paxillin,thereby regulating cell motility and localization of PXN/paxillin . Catalyzes ubiquitination of Salmonella type III secreted protein sopA . Mediates the ''Lys-63''-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N . Mediates the ''Lys-48''-linked polyubiquitination of STING1 at ''Lys-150'' leading to its proteasomal degradation; the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses . Catalyzes ubiquitination and subsequent degradation of ATG4B, thereby inhibiting autophagy . .

E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1),RNF5 G16 NG2 RMA1

Q99942,O35445,Q5M807

6048

Human,Mouse,Rat

WB,ELISA

WB 1:500-2000
ELISA 1:5000-20000

RNF5 Polyclonal Antibody detects endogenous levels of protein.

19kDa

Rabbit

Synthesized peptide derived from part region of human protein

Polyclonal

Rabbit,IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

1 mg/ml

Store at -20℃. Stable for 12 months from date of receipt.