Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits . KCNE2 beta subunit modulates the gating kinetics and enhances stability of the channel complex . Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit . Associates with KCNH2/HERG alpha subunit Kv channel to form the rapidly activating component of the delayed rectifying potassium current (IKr) in heart . May associate with KCNQ2 and/or KCNQ3 alpha subunits to modulate the native M-type current . May associate with HCN1 and HCN2 channel subunits to increase potassium current (By similarity). Forms a heterooligomer complex with KCNQ1/KVLQT1 alpha subunits which leads to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current . KCNQ1-KCNE2 channel associates with Na(+)-coupled myo-inositol symporter in the apical membrane of choroid plexus epithelium and regulates the myo-inositol gradient between blood and cerebrospinal fluid with an impact on neuron excitability (By similarity). .

Potassium voltage-gated channel subfamily E member 2 (MinK-related peptide 1) (MiRP1) (Minimum potassium ion channel-related peptide 1) (Potassium channel subunit beta MiRP1),KCNE2

Q9Y6J6,Q9D808,P63161

9992

Human,Mouse,Rat

WB,ELISA

WB 1:500-2000
ELISA 1:5000-20000

KCNE2 Polyclonal Antibody detects endogenous levels of protein.

13kDa

Rabbit

Synthesized peptide derived from human protein . at AA range: 30-110

Polyclonal

Rabbit,IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

1 mg/ml

Store at -20℃. Stable for 12 months from date of receipt.