PR31532

货号 规格 价格(¥)
PR31532S 50ul
PR31532M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-E2F-1 (phospho Thr433) Antibody

Datasheet

Description

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5''-TTTC[CG]CGC-3'' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication . The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase . E2F1 binds preferentially RB1 in a cell-cycle dependent manner . It can mediate both cell proliferation and TP53/p53-dependent apoptosis . Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters . Directly activates transcription of PEG10 . Positively regulates transcription of RRP1B . .

Alternative Names

Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1),E2F1 RBBP3

Uniprot

Q01094,Q61501

Gene ID

1869/13555

Reactivity

Human,Mouse

Application Image

Application

WB,ELISA

Recommended Dilution

WB 1:500-2000
ELISA 1:5000

Specificity

Phospho-E2F-1 (T433) Polyclonal Antibody detects endogenous levels of E2F-1 protein only when phosphorylated at T433.

Mol Weight

60kDa

Source

Rabbit

Immunogen

Synthesized peptide derived from human E2F1 around the phosphorylation site of Thr433.

Clonality

Polyclonal

Clone No.

Isotype

Rabbit,IgG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Concentration

1 mg/ml

Storage

Store at -20℃. Stable for 12 months from date of receipt.

Antigen retrieval

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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