PR23089

货号 规格 价格(¥)
PR23089S 50ul
PR23089M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Gasdermin C Antibody

Datasheet

Description

[Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering pyroptosis. .; [Gasdermin-C, N-terminal]: Pore-forming protein that causes membrane permeabilization and pyroptosis . Produced by the cleavage of gasdermin-C by caspase CASP8 in response to death signals . After cleavage, moves to the plasma membrane where it strongly binds to membrane inner leaflet lipids . Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis . .

Alternative Names

Gasdermin-C (Melanoma-derived leucine zipper-containing extranuclear factor) [Cleaved into: Gasdermin-C, N-terminal (GSDMC-NT); Gasdermin-C, C-terminal (GSDMC-CT)],GSDMC MLZE

Uniprot

Q9BYG8,Q99NB5

Gene ID

56169

Reactivity

Human,Rat,Mouse

Application Image

Application

WB,IHC,IF,ICC,ELISA

Recommended Dilution

WB 1:500-2000
IHC 1:100-300
IF 1:50-200
ICC 1:50-200
ELISA 1:5000-20000

Specificity

Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein.

Mol Weight

55kDa

Source

Rabbit

Immunogen

The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158

Clonality

Polyclonal

Clone No.

Isotype

Rabbit,IgG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Concentration

1 mg/ml

Storage

Store at -20℃. Stable for 12 months from date of receipt.

Antigen retrieval

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北方及西南经销商负责:

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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