Adhesion G-protein coupled receptor (aGPCR) for androgen hormone 5alpha-dihydrotestosterone (5alpha-DHT), also named 17beta-hydroxy-5alpha-androstan-3-one, the most potent hormone among androgens . Also activated by methenolone drug . Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase . ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity . Acts as a 5alpha-DHT receptor in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength . .

Adhesion G-protein coupled receptor D1 (G-protein coupled receptor 133) (G-protein coupled receptor PGR25) [Cleaved into: Adhesion G-protein coupled receptor D1, N-terminal fragment (ADGRD1 N-terminal fragment); Adhesion G-protein coupled receptor D1, C-terminal fragment (ADGRD1 C-terminal fragment)],ADGRD1 GPR133 PGR25

Q6QNK2

283383

Human,Monkey

WB,IHC,IF,ICC,ELISA

WB 1:500-2000
IHC 1:200-1:1000
IF 1:50-200
ICC 1:50-200
ELISA 1:5000

GPR133 Polyclonal Antibody detects endogenous levels of GPR133 protein.

96kDa

Rabbit

The antiserum was produced against synthesized peptide derived from human GPR133. AA range:461-510

Polyclonal

Rabbit,IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1 mg/ml

Store at -20℃. Stable for 12 months from date of receipt.