13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Acts as a regulatory protein involved in the regulation of numerous cellular processes . Together with its homolog TMC6/EVER1, forms a complex with calcium-binding protein CIB1 in lymphocytes and keratynocytes where TMC6 and TMC8 stabilize CIB1 levels and reciprocally . Together with TMC6, also forms a complex with and activates zinc transporter ZNT1 at the ER membrane of keratynocytes, thereby facilitating zinc uptake into the ER . Also inhibits receptor-mediated calcium release from ER stores and calcium activated and volume regulated chloride channels . Down-regulates the activity of transcription factors induced by zinc and cytokines . Also sequesters TRADD which impairs the recruitment of TRAF2 and RIPK1 in the pro-survival complex I and promotes proapoptotic complex II formation, and may therefore be involved in TNF-induced cell death/survival decisions . .
Transmembrane channel-like protein 8 (Epidermodysplasia verruciformis protein 2),TMC8 EVER2 EVIN2
Q8IU68,Q7TN58
147138/217356
Human,Mouse,Rat
WB,IHC,IF,ICC,ELISA
WB 1:500-2000IHC 1:50-300IF 1:50-200ICC 1:50-200ELISA 1:5000
TMC8 Polyclonal Antibody detects endogenous levels of TMC8 protein.
81kDa
Rabbit
Synthesized peptide derived from human TMC8.
Polyclonal
Rabbit,IgG
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
1 mg/ml
Store at -20℃. Stable for 12 months from date of receipt.
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应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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