High-affinity sodium/citrate cotransporter that mediates the entry of citrate into cells, which is a critical participant of biochemical pathways . May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis . Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form . Can recognize succinate as a substrate, but its affinity for succinate is several fold lower than for citrate . The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic . Involved in the regulation of citrate levels in the brain (By similarity). .

Na(+)/citrate cotransporter (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter) (Solute carrier family 13 member 5),SLC13A5 NACT

Q86YT5,Q67BT3,Q8CJ44

284111/237831/266998

Human,Mouse,Rat

WB

WB 1:500-2000

This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat

60kDa

Rabbit

Synthesized peptide derived from human S13A5 AA range: 313-363

Polyclonal

Rabbit,IgG

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1 mg/ml

Store at -20℃. Stable for 12 months from date of receipt.