PR15338

货号 规格 价格(¥)
PR15338S 50ul
PR15338M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-TMX1 Antibody

Datasheet

Description

Thiredoxin domain-containing protein that participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions . Acts as a key inhibitor of the alternative triglyceride biosynthesis pathway by inhibiting the activity of TMEM68/DIESL at the endoplasmic reticulum, thereby restricting accumulation of triacylglycerol . The alternative triglyceride biosynthesis pathway mediates formation of triacylglycerol from diacylglycerol and membrane phospholipids . Acts as a protein disulfide isomerase by catalyzing formation or reduction of disulfide bonds . Specifically mediates formation of disulfide bonds of transmembrane proteins at the endoplasmic reticulum membrane . Involved in endoplasmic reticulum-associated degradation (ERAD) via its protein disulfide isomerase activity by acting on folding-defective polypeptides at the endoplasmic reticulum membrane . Acts as a negative regulator of platelet aggregation following secretion in the extracellular space . Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals . Regulates endoplasmic reticulum-mitochondria Ca(2+) flux . .

Alternative Names

Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein),TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268

Uniprot

Q9H3N1,Q8VBT0

Gene ID

81542/72736

Reactivity

Human,Mouse

Application Image

Application

WB

Recommended Dilution

WB 1:500-2000

Specificity

This antibody detects endogenous levels of TMX1 at Human/Mouse

Mol Weight

31kDa

Source

Rabbit

Immunogen

Synthesized peptide derived from human TMX1 AA range: 223-273

Clonality

Polyclonal

Clone No.

Isotype

Rabbit,IgG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Concentration

1 mg/ml

Storage

Store at -20℃. Stable for 12 months from date of receipt.

Antigen retrieval

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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
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华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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