PR61400

货号 规格 价格(¥)
PR61400S 50ul
PR61400M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

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   免疫荧光

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   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-DNA pol β (Acetyl Lys72) Antibody

Datasheet

Description

Repair polymerase that plays a key role in base-excision repair . During this process, the damaged base is excised by specific DNA glycosylases, the DNA backbone is nicked at the abasic site by an apurinic/apyrimidic (AP) endonuclease, and POLB removes 5''-deoxyribose-phosphate from the preincised AP site acting as a 5''-deoxyribose-phosphate lyase (5''-dRP lyase); through its DNA polymerase activity, it adds one nucleotide to the 3'' end of the arising single-nucleotide gap . Conducts ''gap-filling'' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. It is also able to cleave sugar-phosphate bonds 3'' to an intact AP site, acting as an AP lyase . .

Alternative Names

DNA polymerase beta (EC 2.7.7.7) (5''-deoxyribose-phosphate lyase) (5''-dRP lyase) (EC 4.2.99.-) (AP lyase) (EC 4.2.99.18),POLB

Uniprot

P06746,Q8K409,P06766

Gene ID

5423/18970/29240

Reactivity

Human,Mouse,Rat

Application Image

Application

WB,ELISA

Recommended Dilution

WB 1:500-2000
ELISA 1:5000-20000

Specificity

This antibody detects endogenous levels of Human,Mouse,Rat DNA pol β (Acetyl Lys72)

Mol Weight

38kDa

Source

Rabbit

Immunogen

Synthesized peptide derived from human DNA pol β (Acetyl Lys72)

Clonality

Polyclonal

Clone No.

Isotype

Rabbit,IgG

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Concentration

1 mg/ml

Storage

Store at -20℃. Stable for 12 months from date of receipt.

Antigen retrieval

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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