13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5''-untranslated region, and locates the initiation codon . In this complex, acts as a GTPase-activating protein, by promoting GTP hydrolysis by eIF2G (EIF2S3) . During scanning, interacts with both EIF1 (via its C-terminal domain (CTD)) and EIF1A (via its NTD) . This interaction with EIF1A contributes to the maintenance of EIF1 within the open 43S PIC . When start codon is recognized, EIF5, via its NTD, induces eIF2G (EIF2S3) to hydrolyze the GTP . Start codon recognition also induces a conformational change of the PIC to a closed state . This change increases the affinity of EIF5-CTD for EIF2-beta (EIF2S2), which allows the release, by an indirect mechanism, of EIF1 from the PIC . Finally, EIF5 stabilizes the PIC in its closed conformation . .
Eukaryotic translation initiation factor 5 (eIF-5),EIF5
P55010,P59325,Q07205
1983/100047658/56783
Human,Mouse,Rat
WB
WB 1:500-2000
This antibody detects endogenous levels of EIF5 (Phospho-Ser389+Ser390) at Human, Mouse,Rat
50kDa
Rabbit
Polyclonal
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
1 mg/ml
Store at -20℃. Stable for 12 months from date of receipt.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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