13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5''-end of an NAD-capped RNA . The NAD-cap is present at the 5''-end of some RNAs and snoRNAs . In contrast to the canonical 5''-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay . Preferentially acts on NAD-capped transcripts in response to environmental stress . Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation (By similarity). Specifically degrades pre-mRNAs with a defective 5''-end m7G cap and is part of a pre-mRNA capping quality control (By similarity). Has decapping activity toward incomplete 5''-end m7G cap mRNAs such as unmethylated 5''-end-capped RNA (cap0), while it has no activity toward 2''-O-ribose methylated m7G cap (cap1) . In contrast to canonical decapping enzymes DCP2 and NUDT16, which cleave the cap within the triphosphate linkage, the decapping activity releases the entire cap structure GpppN and a 5''-end monophosphate RNA (By similarity). Also has 5''-3'' exoribonuclease activities: The 5''-end monophosphate RNA is then degraded by the 5''-3'' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs . Also possesses RNA 5''-pyrophosphohydrolase activity by hydrolyzing the 5''-end triphosphate to release pyrophosphates (By similarity). Exhibits decapping activity towards FAD-capped RNAs . Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity). .
Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5''-3'' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-),DXO DOM3L DOM3Z NG6
O77932,O70348,Q6MG77
1797/112403/361799
Human,Mouse,Rat
WB
WB 1:500-2000
This antibody detects endogenous levels of DOM3Z at Human, Mouse,Rat
44kDa
Rabbit
Polyclonal
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
1 mg/ml
Store at -20℃. Stable for 12 months from date of receipt.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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