Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Required for maintenance of chromosomal stability . Promotes accurate and efficient pairing of homologs during meiosis . Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing . The FANCI-FANCD2 complex binds and scans double-stranded DNA (dsDNA) for DNA damage; this complex stalls at DNA junctions between double-stranded DNA and single-stranded DNA (By similarity). May participate in S phase and G2 phase checkpoint activation upon DNA damage . Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress . Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress . Promotes BRCA2/FANCD1 loading onto damaged chromatin . May also be involved in B-cell immunoglobulin isotype switching. .
Fanconi anemia group D2 protein (Protein FACD2),FANCD2 FACD
Q9BXW9,Q80V62,Q6IV68
2177/211651/312641
Human,Mouse,Rat
WB,IHC
WB 1:500-2000IHC 1:50-200
This antibody detects endogenous levels of FANCD2 (Phospho Thr691) Rabbit pAb at Human, Mouse,Rat
166kDa
Rabbit
Polyclonal
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
1 mg/ml
Store at -20℃. Stable for 12 months from date of receipt.
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