PR33074

货号 规格 价格(¥)
PR33074S 50ul
PR33074M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-FANCD2 (Phospho Thr691) Antibody

Datasheet

Description

Required for maintenance of chromosomal stability . Promotes accurate and efficient pairing of homologs during meiosis . Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing . The FANCI-FANCD2 complex binds and scans double-stranded DNA (dsDNA) for DNA damage; this complex stalls at DNA junctions between double-stranded DNA and single-stranded DNA (By similarity). May participate in S phase and G2 phase checkpoint activation upon DNA damage . Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress . Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress . Promotes BRCA2/FANCD1 loading onto damaged chromatin . May also be involved in B-cell immunoglobulin isotype switching. .

Alternative Names

Fanconi anemia group D2 protein (Protein FACD2),FANCD2 FACD

Uniprot

Q9BXW9,Q80V62,Q6IV68

Gene ID

2177/211651/312641

Reactivity

Human,Mouse,Rat

Application Image

Application

WB,IHC

Recommended Dilution

WB 1:500-2000
IHC 1:50-200

Specificity

This antibody detects endogenous levels of FANCD2 (Phospho Thr691) Rabbit pAb at Human, Mouse,Rat

Mol Weight

166kDa

Source

Rabbit

Immunogen

Clonality

Polyclonal

Clone No.

Isotype

Purification

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

Concentration

1 mg/ml

Storage

Store at -20℃. Stable for 12 months from date of receipt.

Antigen retrieval

艾比玛特医药科技(上海)有限公司
上海市徐汇区桂平路333号聚科生物园区1号楼1-3层

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北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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