13916964679
Note: Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.
注意：抗体应用为IHC的，抗体只适合于石蜡切片的组化染色或者荧光染色。
抗体应用为IF/ICC的，抗体适合于冰冻切片的组化染色或者荧光染色，以及细胞水平的化学染色和荧光染色。
ABMART实验方案下载
Transcription factor that acts as a master regulator of melanocyte survival and differentiation as well as melanosome biogenesis . Binds to M-boxes (5''-TCATGTG-3'') and symmetrical DNA sequences (E-boxes) (5''-CACGTG-3'') found in the promoter of pigmentation genes, such as tyrosinase (TYR) . Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, MITF phosphorylation by MTOR promotes its inactivation . Upon starvation or lysosomal stress, inhibition of MTOR induces MITF dephosphorylation, resulting in transcription factor activity . Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) . Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium . .
Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32),MITF BHLHE32
O75030,Q08874
4286/17342
Human,Mouse,Rat
WB,IHC,IF,ICC,ELISA
WB 1:1000-5000IHC 1:200-500IF 1:100-1:400ICC 1:100-1:400ELISA 1:5000-20000
58kDa
Rabbit
Monoclonal
X2034
Monoclonal, rabbit, IgG, Kappa
Protein A
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Store at -20℃. Stable for 12 months from date of receipt.
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邮箱：market@ab-mart.com
应聘职位：hr@ab-mart.com
订购专线：4006-123-828
销售电话：13916964679（微信同号）
技术支持：15618194176（微信同号）
华南经销商负责（广东，广西，福建，海南）：
程经理：手机18616261485（微信同号）
华北经销商负责（北京，天津，河北）：
徐经理：手机15618191473（微信同号）
南方经销商负责：
陆经理：手机13122837132（微信同号）
北方及西南经销商负责：
张经理：手机13122150513（微信同号）
微信客服
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