Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)) . Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1'')-Cer . Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P . .; (Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins. .

q9npc4

Lactosylceramide 4-alpha-galactosyltransferase (EC 2.4.1.228) (Alpha-1,4-N-acetylglucosaminyltransferase) (Alpha-1,4-galactosyltransferase) (Alpha4Gal-T1) (CD77 synthase) (Globotriaosylceramide synthase) (Gb3 synthase) (P1/Pk synthase) (UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase),A4GALT A14GALT A4GALT1,Gb3 synthase,UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase,CD77 synthase,Alpha-1,4-N-acetylglucosaminyltransferase,Lactosylceramide 4-alpha-galactosyltransferase,Alpha4Gal-T1,Alpha-1,4-galactosyltransferase,A4GALT1,A4GALT,Globotriaosylceramide synthase,P1/Pk synthase,A14GALT

Human, Rat

WB,IHC,ELISA

WB 1:500-1:2000
IHC 1:50-1:300
ELISA 1:5000-1:20000

41kD

Rabbit

Recombinant Human CD77/A4GALT (Gly44-Leu353).

Polyclonal

IgG

Purified by antigen affinity column.

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.