PJH753646

货号 规格 价格(¥)
PJH753646S 50ul
PJH753646M 100ul

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Note:  Application as IHC, only suitable for histochemical staining or fluorescence staining of paraffin-embedded sections. Application as ICC/IF, suitable for histochemical or fluorescent staining of frozen sections, as well as chemical and fluorescent staining at the cellular level.

注意:抗体应用为IHC的,抗体只适合于石蜡切片的组化染色或者荧光染色。

抗体应用为IF/ICC的,抗体适合于冰冻切片的组化染色或者荧光染色,以及细胞水平的化学染色和荧光染色。

ABMART实验方案下载

   蛋白质免疫共沉淀

   蛋白质印迹

   免疫荧光

   免疫组化

   膜再生

   植物BPP法变性蛋白提取

   组织制备成单细胞悬液

经典一抗-Human ALKBH4 Antibody

Datasheet

Background

Description

Dioxygenase that mediates demethylation of actin monomethylated at ''Lys-84'' (K84me1), thereby acting as a regulator of actomyosin-processes . Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration . In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing (By similarity). .

Uniprot

q9nxw9

Alternative Names

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-),ALKBH4 ABH4,ALKBH4, Lysine-specific demethylase ALKBH4, DNA N6-methyl adenine demethylase ALKBH4, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4, ABH4, Alkylated DNA repair protein alkB homolog 4

Specificity

Application Image

Reactivity

Human

Application

WB,IHC,ELISA

Recommended Dilution

WB 1:500-1:2000
IHC 1:50-1:300
ELISA 1:5000-1:20000

Mol weight

34kD

Conjugation

Source

Rabbit

Immunogen

Recombinant Human ALKBH4 (Thr8-Val302).

Clonality

Polyclonal

Clone No.

Isotype

IgG

Purification

Purified by antigen affinity column.

Purity

Buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Concentration

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4℃ short term (1-2 weeks). Store at -20℃ 12 months.

Note

艾比玛特医药科技(上海)有限公司
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技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
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华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

邮箱:market@ab-mart.com

应聘职位:hr@ab-mart.com

订购专线:4006-123-828

销售电话:13916964679(微信同号)

技术支持:15618194176(微信同号)

华南经销商负责(广东,广西,福建,海南):
程经理:手机18616261485(微信同号)
华北经销商负责(北京,天津,河北):
徐经理:手机15618191473(微信同号)
南方经销商负责:

陆经理:手机13122837132(微信同号)
北方及西南经销商负责:

张经理:手机13122150513(微信同号)

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      微信客服

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